ToxiDex is FlashPath's core data product: a large-scale, harmonized toxicology dataset built to support modern analysis, modeling, and interpretation of safety data. It aggregates fragmented legacy datasets at the individual-animal level, enabling cross-study comparisons that are not possible using raw source files.

Framework & Utility

What ToxiDex Is

  • Cleaned & Harmonized Data: Millions of individual-animal records standardized across studies, species, and data modalities.
  • Foundational Infrastructure: A unified data foundation designed for cross-study, cross-compound analysis at scale.
  • Analysis-Ready Structure: Delivered in structured tables or via database/API, optimized for lesion-, organ-, and chemical-level enrichment.

What ToxiDex Is Not

  • Not a Model: ToxiDex is training and analysis data, not the final AI tool.
  • Not a Decision System: It is not a standalone regulatory or decision-making tool.

Data Coverage (V1)

Histopathology

Annotated findings and lesion-level pathology data across 650k+ animal records.

Survival Data

Longitudinal mortality outcomes and study metadata for long-term safety analysis.

Clinical Profiles

Chemistry, hematology, and organ weights standardized for statistical modeling.

Chemical Meta

Structural annotations and fingerprints linked directly to toxicological outcomes.

Toxicology Data Sources

ToxiDex integrates multiple widely used toxicology resources that were originally distributed across heterogeneous formats and study designs. FlashPath standardizes these datasets at the individual-animal level to enable cross-study comparison and downstream modeling.

National Toxicology Program (NTP / CEBS)

Acute, subchronic, and chronic rodent toxicology and carcinogenicity studies with pathology annotations, clinical chemistry, clinical observations, survival data, and additional data modalities.

TG-GATEs

Short- and sub-chronic toxicogenomics studies linking transcriptomics with pathology and clinical chemistry.

DrugMatrix

Systematic, multi-organ toxicology studies across doses linking to transcriptomics, pathology, and clinical chemistry.